

Secondary adrenal insufficiency is more common than primary adrenal insufficiency. genetic disorders that affect pituitary gland function.bleeding in or around the pituitary gland.cancer that affects the pituitary gland.Potential causes of secondary adrenal insufficiency include: As such, when the pituitary gland doesn’t make enough ACTH, the adrenal glands won’t make enough cortisol. ACTH is what tells your adrenal glands to make cortisol. One function is to make a hormone called adrenocorticotropin (ACTH). The pituitary gland is found at the base of your brain and has many important functions. Secondary adrenal insufficiency happens when there’s a problem with the pituitary gland. It happens more frequently in females, with most diagnoses made between the ages of 30 and 50. Researchers estimate that primary adrenal insufficiency affects 82 to 144 per 1 million people. specific medications, such as certain antifungals and the anesthesia drug etomidate.genetic disorders that affect adrenal gland function.surgery that removes all or part of the adrenal glands.


